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New theory shows how adrenal weakness can cause blood acidity and calcium problems


Monday, April 22 2002 - Filed under: General

Hi,

The adrenal-support supplements are working very well: The brain fogs are virtually gone and I feel a *lot* better..
I just figured out something else: how a weak adrenal gland might cause the calcium imbalance I'm experiencing:

1 ua1vm.ua.edu/~shancock/NHM101/Minerals.PDF
2 www.howstuffworks.com/kidney7.htm

Low adrenal output means low aldosteron
Low aldosteron means potassium retention and sodium excretion
Low sodium means problems maintaining fluid and electrolyte balance 1
Low sodium also means problems maintaining acid-base balance 1

Details of problems with maintaining acid-base balance:
The kidneys regulate the acid-base balance in the blood 2:
''Your blood maintains a constant concentration of hydrogen ion (pH) by a chemical mixture of hydrogen ions and sodium bicarbonate.''

''The correct pH is maintained by keeping the ratio of hydrogen ion to bicarbonate in the blood constant. If you add acid (hydrogen ion) to the blood, then you will reduce the
bicarbonate concentration and alter the pH of the blood. Similarly, if you reduce the hydrogen ion by adding alkali, you will increase the bicarbonate concentration and alter the
pH of the blood. ''

pH is inverse log of H+-concentration, meaning:
High pH = alkalic blood = Low H+ concentration
Low pH = acidic blood = High H+ concentration

How the kidneys increase acidity (lower pH, increase H+):
CO2 + H2O ----> H2CO3 ----> H+ + HCO3-

How the kidneys decrease acidity (increase pH, decrease H+):
H+ + NaHCO3 ---> H2CO3 + Na ---> CO2 + H2O

Thus:
The kidneys transform water + carbondioxide into hydrogen ions (and some other stuff), thus raising acidity.
The kidneys transform ''H+'' + *sodium*bicarbonate back to water + carbondioxide, thus lowering acidity.

The 2nd process, the lowering of acidity depends on sodium.. What might happen when sodium levels are low in the blood, due to low aldosterone ? Bad buffering capacity
after eating acidic foods.. The blood tends to get acidic and the body compensates by dissolving calcium to lower acidity.. In the process the serum calcium levels get too high,
bones start to deteriorate and magnesium-deficiency symptoms start to show (magnesium is calcium's antagonist and vice versa)..

Some further suggestive proof:

www.merck.com/pubs/mm_geriatrics/sec8/ch59.htm
''Metabolic Alkalosis: ....
In these cases, the *mineralocorticoid excess* dictates excessive renal generation of bicarbonate because of stimulated sodium/hydrogen exchange..''

Let's turn this around and we get:

''Metabolic Acidosis:
In these cases the mineral corticoid deficiency dicates low renal generation of bicarbonate because of depressed sodium/hydrogen exchange..''

Interesting, eh ?

This info might be very interesting with regards to depression, hypglycemia, and other things that are magnesium-calcium-related.. In the end they might all be adrenal-related
problems..

I've updated my hypoglycemia article in which I identify three different types of hypoglycemia.. I think you might find that interesting too:
www.newtreatments.org/hypo.php
* Hypoglycemia due to Insulin Resistance
* Hypoglycemia due to Adrenal Fatigue
* Hypoglycemia due to yeast metabolites

Let me know what you think of these theories..

Thanks,

Ed,
The Netherlands



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